The Games Company (TGC) have announced Afterfall: Insanity for "PC and next-gen consoles" (4,5 years into the generation it's still next apparently). It's set in the Afterfall universe, that bears an uncanny resemblance to the Fallout universe (not just the fall). The premise is that Afterfall is what's left after the nuclear holocaust of 2012 (set your alarms!) and now mutants and mercenaries fight decent God fearing individuals in the wastelands and shelters.
The game is set for release in early 2011, so you will be able to play it before the mutants come for your brains!