According to the CV of a 3D artist (captured by VideoGamer, Del Toro's production company, Mirada Studios, has worked with publisher Bethesda to create a "Fallout 4 cinematic trailer".
The studio has worked with Disney, Nike and Katy Perry, and the artist in question has worked on several high end game trailers, so this certainly lends credence to a reveal of Fallout 4 very soon. Perhaps... at E3?