There is no stopping the tidal wave that is Grand Theft Auto V. Take Two has announced that is has passed 45 million sold (shipped) copies, and that makes it second only to Wii Sports when it comes to the best selling full-priced video games (mobile games like Tetris and cheaper titles like Minecraft not included) in the world.
And Wii Sports was, of course, bundled with Wii everywhere but Japan and it's therefore fair to say that it is in fact the best selling title ever.